Most Popular Articles

Don’t want to miss a thing? We get that. Here’s every article we’ve reviewed, in descending order by number of views:

• ACCP Guidelines for Diagnosis and Management of DVT/PE/VTE, 9th edition (Review)
• Surviving Sepsis Guidelines Updated: Preview from SCCM Meeting
• How to manage anticoagulation perioperatively (ACCP Recommendations)
• Mechanical Ventilation in ARDS: 2012 Update
• How to start & manage warfarin/coumadin for acute DVT/PE (ACCP Recs)
• Treating acute pulmonary embolism with anticoagulant therapy (ACCP Guidelines)
• Chronic obstructive pulmonary disease 2012 update (COPD Review, Lancet)
• Meet the New ARDS: Expert panel announces new definition, severity classes (JAMA)
• Initial Treatment of Acute Deep Venous Thrombosis (DVT) of the Leg (ACCP/Chest Guidelines)
• Preventing DVT and PE in hospitalized medical patients (Guideline, ACCP Recs)
• Diagnosis of Lower-Extremity DVT (ACCP/Chest Guidelines)
• Thrombolytics for acute pulmonary embolism (ACCP Guidelines)
• Inferior vena cava filters for acute PE and DVT (ACCP Guidelines)
• Interpreting high troponin: It’s not just for cardiologists anymore (Review, Circulation)
• Prevention and Treatment of DVT/PE in Pregnant Women (ACCP/Chest Guidelines)
• Idiopathic Pulmonary Fibrosis 2012 Update (Reviews, Lancet & Thorax)
• Precedex as good as Versed or Propofol, but with cardiovascular effects (RCT, JAMA)
• Diaphragmatic dysfunction and respiratory illness (Review, NEJM)
• Treatment of Acute Deep Vein Thrombosis (DVT) of the Arm (Review/Guideline, Chest)
• Pain control and sedation in mechanically ventilated patients (Review, AJRCCM)
• Anemia in the ICU: 2012 Update (Review, AJRCCM)
• Pneumonia and Respiratory Infections: 2012 Update (Review, AJRCCM)
• An aspirin a day keeps recurrent DVT and PE away (RCT, NEJM)
• Can procalcitonin help guide therapy for suspected pneumonia & other infections? (Review, Chest)
• Should lactate clearance replace SvO2 in sepsis protocols? (Pro/Con, CHEST)
• Antibiotics (azithromycin) to prevent COPD exacerbations (Review, NEJM)
• Sedation vacations don’t improve outcomes in large trial (RCT, JAMA)
• FDA approves Aclidinium (Tudorza Pressair), a b.i.d. “me-too” to Spiriva for COPD
• Ventilator bundles (VAP bundles) not evidence-based, shouldn’t be standard care (JAMA)
• New GOLD guidelines: Better than the old GOLD
• Sharpen your eye with these free online radiology tutorials
• Xarelto (rivaroxaban) gets FDA indication for DVT and PE; no heparin bridging needed
• Oral rivaroxaban (Xarelto) noninferior to warfarin for PE (RCT, NEJM)
• Hyperosmolar Therapy for Increased Intracranial Pressure (Review, NEJM)
• Non-ST elevation myocardial infarction & unstable angina (Review, AJRCCM)
• Managing severe PH and right heart failure in the ICU (Review, AJRCCM)
• Tobin: “Minimal” PEEP and pressure support during SBT kills some patients (AJRCCM)
• Azithromycin associated with cardiovascular death (NEJM)
• Alpha-1 antitrypsin deficiency: what you need to know (Review, AJRCCM)
• Weaning from Mechanical Ventilation Update (Review, NEJM)
• Normal saline: toxic to kidneys? Chloride solutions may cause renal failure (JAMA)
• Tranexamic acid saves lives, reduces transfusions. So why does no one use it? (Review, BMJ)
• Hydroxyethyl starches kill people with severe sepsis; use crystalloid instead (RCT, NEJM)
• Supraventricular Tachycardia (SVT): Initial Diagnosis and Treatment (Review, NEJM)
• Pulmonary Hypertension Update, Part 1: Classification & Diagnosis (Review, JAMA)
• ECMO for severe ARDS (Review, NEJM)
• Femoral lines might not be so bad after all for infection risk (Crit Care Med)
• What the U.S. government doesn’t want you to know: e-cigarettes work (BMC Public Health)
• Pneumothorax in the ICU (Review, Chest)
• Managing opioid overdose in the ICU (Review, NEJM)
• ACP advises against universal DVT/PE prophylaxis! “Quality” quagmire thickens (Guideline/Review, Ann Intern Med)
• Enoxaparin prophylaxis: no effect on mortality or fatal pulmonary embolism (RCT, NEJM)
• Hypersensitivity Pneumonitis 2012 Update (Review, Chest)
• Restrictive fluid management for ARDS saves lungs, but does it also fry brains? (AJRCCM)
• How to work up pulmonary nodules in the new era (Review, AJRCCM)
• New IPF staging and prognosis model announced (Ann Intern Med)
• Come One, Come All – Low tidal volumes improve outcomes (JAMA)
• Forget “embolic burden” of pulmonary embolism: location is everything (Chest)
• Passive leg raise offers promise in predicting fluid responsiveness (Chest)
• Gabapentin worked for chronic cough — thank goodness, something did (RCT, Lancet)
• American Lung Association recommends CT screening for lung cancer
• Bronchial thermoplasty for refractory asthma (Review, AJRCCM)
• At treating asthma, patients may be as good as their doctors (BASALT trial, JAMA)
• Pulmonary Hypertension / Pulmonary Vascular Disease: 2012 Update (Review, AJRCCM)
• Using BNP-guided algorithm meant faster ventilator weaning (RCT, AJRCCM)
• Blood transfusion harmful, even deadly, in some patients with GI bleeds (RCT, NEJM)
• Intensive glucose control probably kills, says NICE-SUGAR post-hoc (NEJM)
• Systemic steroids for severe sepsis and septic shock (Review, AJRCCM)
• Pulmonary Vasculitis Update Part 1: Clinical Features & Diagnosis (Review, AJRCCM)
• Intubation & Airway Management Review (LITFL)
• FDA warns of sudden cardiac death with use of azithromycin
• PANTHER-IPF negative, stopped early for harm from steroids, Imuran in IPF (RCT, NEJM)
• Using bronchoalveolar lavage to evaluate ILD (ATS Guideline, AJRCCM)
• Predicting survival from COPD exacerbations: DECAF score shows promise (Thorax)
• PET scans often inaccurate; may deny curative surgery for lung cancer
• Adding tiotropium (Spiriva) helped some with uncontrolled asthma (RCT, NEJM)
• Go back to bed; overnight intensivists don’t reduce mortality (NEJM)
• Continuing beta blockers safe during acute COPD exacerbations (Thorax)
• FDA approves ivacaftor (Kalydeco), new cystic fibrosis drug (Guess what it costs?)
• What works to help people with pulmonary fibrosis feel better? (Review, Thorax)
• Cystic Fibrosis 2012 Update (Review, AJRCCM)
• Xigris’ epitaph: “I Never Worked a Day in My Life” (PROWESS-SHOCK, NEJM)
• ACCP, ATS only weakly recommend lung cancer CT screening, warn of harms (JAMA)
• Trophic feeding equal to full enteric feeding in acute lung injury (EDEN trial, JAMA)
• Non-small cell lung cancer (NSCLC): Advances in Diagnosis and Treatment (Update/Review)
• Azithromycin reduces exacerbations in non-CF bronchiectasis (RCT, Lancet)
• Moderate pot smokers’ lung function better than nonsmokers (JAMA)
• Amoxicillin speeds resolution of acute sinus infections, but imperceptibly? (RCT, JAMA)
• New lung tissue growth can occur in adults, defying previous belief (NEJM)
• Pleural catheters equal to pleurodesis for dyspnea relief from malignant effusions (TIME2, JAMA)
• Drowning: 2012 Update (Review, NEJM)
• Time to retire routine replacement of peripheral IVs (Lancet)
• Using procalcitonin to guide antibiotics for pneumonia (JAMA)
• Hydroxyethyl starch fries kidneys in another large trial (RCT, NEJM)
• Pulmonary Hypertension Update, Part 2: Treatment of PH (Review, JAMA)
• Pulse oximetry as time machine: Lag times confuse doctors, complicate intubations (EMCrit)
• Diuretics beat ultrafiltration at treating congestive heart failure with acute renal failure (RCT, NEJM)
• Chronic cough isn’t all in your head — only part of it is (Chest)
• Does your COPD patient need in-flight oxygen? New algorithm may help (Thorax)
• Post-pyloric feeding no better than usual NG tube in vented patients (RCT, Crit Care Med)
• COPD surprise: In majority, FEV1 declines no faster than healthy people’s (NEJM)
• How to take care of older people with COPD (Review, JAMA)
• High frequency oscillation ventilation fails as 1st-line treatment for ARDS (RCTs, NEJM)
• Superior Vena Cava Syndrome (Cancer-Related Medical Emergencies Review, Crit Care Med)
• Having a pulmonary embolism? Don’t wait for the weekend (Chest)
• FEV1 decline varies widely in COPD, another cohort confirms (AJRCCM)
• “Trach collar” beats pressure support trials for long-term ventilator weaning (RCT, JAMA)
• Does GERD really cause chronic cough? (Chest)
• Etomidate associated with increased mortality in sepsis: meta-analysis (Crit Care Med)
• Walk to wean: Early mobilization for ventilated patients (Review, CHEST)
• Fever reduction improves early mortality in septic shock? Take a closer look (RCT, AJRCCM)
• Bad news for IP guys? Incidental mediastinal lymphadenopathy may not need routine biopsy (J Thorac Oncol)
• Hope floats: Fecal transplants cure >90% of recurrent C. difficile (RCT, NEJM)
• Adherence with low tidal volumes for ARDS is poor at top centers; reduces survival (BMJ)
• New risk calculator for postoperative respiratory failure (CHEST)
• Pulmonary Vasculitis Update, Part 2: Treatment and Prognosis (Review, AJRCCM)
• In ARDS, women and short people get higher, potentially deadly tidal volumes (Crit Care)
• Inferior vena cava filters: debatable benefit; rarely removed (JAMA Int Med)
• The fight against dogma in critical care
• GERD therapy associated with IPF survival in small study (AJRCCM)
• New auto-weaning ventilator might make pulmonologists obsolete (RCT, AJRCCM)
• PANTHER-IPF stopped early; prednisone + azathioprine don’t work for IPF (Thorax)
• Early tracheostomy doesn’t improve outcomes … much (Meta-analysis, CHEST)
• NYT runs press release for new OSA treatment Provent. Does it work?
• Killer carbapenem-resistant bacteria spreading through LTACs
• Diagnosis of pneumothorax: Ultrasound beats chest X-ray (Meta-analysis, CHEST)
• Assess the IVC for fluid responsiveness with ultrasound (EMCrit Video)
• Drier is better for kidneys, too? In ARF, negative fluid balance associated with survival (Crit Care Med)
• Lung volume reduction coils improve dyspnea, FEV1 in COPD (RCT, Chest Update 2012)
• How many times has giving empiric antibiotics saved your professional behind? (NEJM)
• Should pleurodesis or PleurX drain be 1st-line Rx for malignant pleural effusion? (Pro/Con, Chest)
• How dangerous are ground glass nodules over time? (Chest)
• Diagnosis and Management of Stable COPD: ATS, ACCP, ACP Practice Guideline (Review, Ann Intern Med)
• Tiotropium as add-on “triple therapy” for COPD associated with better outcomes (CHEST)
• Last-Minute Pulmonary and Critical Care Board Review!
• Intubation in pre-hospital cardiac arrest strongly associated with worse outcomes (JAMA)
• Allergic rhinitis update (Review/Guideline, Lancet)
• Do people with pulmonary hypertension need in-flight oxygen? (Chest)
• Singulair (montelukast) goes generic (FDA)
• Eh? What’d you say? Daily azithromycin reduces COPD exacerbations, may cause hearing loss (RCT, NEJM)
• Pirfenidone for idiopathic pulmonary fibrosis (CAPACITY trials, Lancet)
• Advanced bronchoscopy yields are 70% in meta-analysis (Review, Chest)
• Xigris X’d! PROWESS-SHOCK negative; activated protein C yanked from global market
• Survival after in-ICU PEA/asystole cardiac arrest unchanged at 20 yrs (CMAJ)
• For empyema, tPA plus DNAse in the pleural space improved outcomes (RCT, NEJM)
• Air travel for patients with lung disease: Recommendations (Thorax BTS Guideline, Review)
• Intracranial hemorrhage (Concise clinical review, AJRCCM)
• First report of transiently reversible brain death after induced hypothermia (Crit Care Med)
• Bronchoscopy meds: a handy how-to guide (ACCP Guideline/Review, CHEST)
• Fellows: This is your brain on protocols (JAMA)
• Long-acting beta agonist safety for asthma (Review, Thorax)
• In COPD, coexisting CHF is common, underrecognized (and lethal?) (Eur Resp J)
• Sleep Medicine Update: June 2012 (Review)
• FDA approves Breo Ellipta, a new once-daily COPD inhaler treatment
• Anti-reflux therapy no help for most with chronic cough (Chest)
• Sildenafil worked in pulmonary hypertension due to CHF with preserved EF (RCT, Circulation)
• In COPD, larger pulmonary artery assoc. with severe exacerbations (NEJM)
• Exhaled nitric oxide’s clinical applications: ATS Practice Guideline (AJRCCM)
• Successful use of NIPPV for COPD exacerbations rising – but beware (AJRCCM)
• Dutch lung cancer prevention trial shows no benefit of CT screening (RCT, Thorax)
• Bronchodilator reversibility testing in COPD: Bill for it, but don’t believe it (CHEST)
• Bactrim for idiopathic pulmonary fibrosis? Intriguing, but not yet (RCT, Thorax)
• Follow-up chest X-rays after pneumonia? Only for 50-and-up crowd, say Canadians (Arch Int Med)
• Neti pots kill 2 after transmitting brain-eating amoeba
• Virtual bronchoscopy diagnosed 80% of peripheral lung nodules (RCT, Thorax)
• Cancer-Related Medical Emergencies: Tumor Lysis Syndrome (Review, Crit Care Med)
• See CPAP work for OSA in this “explicit” video (NEJM)
• NSCLC: Anti-PD-L1 immunotherapy breaks ground, buys time for some (NEJM)
• Pirfenidone’s long trudge to FDA approval: InterMune launches new trial (ASCEND-3)
• CPAP cures metabolic syndrome in obstructive sleep apnea (RCT, NEJM)
• Work-up of suspected PE in pregnancy (Guideline/Review, AJRCCM)
• Meropenem + moxifloxacin: no improvement over meropenem alone in severe sepsis (RCT, JAMA)
• Stop yelling, dear, you’re hurting Jimmy’s lungs (AJRCCM)
• Allowing families to witness CPR had positive effects (RCT, NEJM)
• Reversing the new anticoagulation drugs: Prothrombin complex could work for rivaroxaban, not dabigatran (Circulation)
• “Practice ischemia” on an arm reduces contrast nephropathy after procedures (RCT, Circulation)
• New atrial fibrillation causes stroke, death in people with severe sepsis? (JAMA)
• Acupuncture improved COPD in a “real” randomized trial (Arch Intern Med)
• Probiotics don’t prevent ventilator-associated pneumonia (Review, Chest)
• Maintenance of board certification needs overhaul, now (Jonathan Weiss)
• Bad Bugs: They don’t call it C. “difficile” for nothing (Review, CHEST)
• Inhaled corticosteroids stunt growth of America’s youth by a half-inch (NEJM)
• Let’s be honest: quitting smoking usually does make you fatter (BMJ)
• CPAP gives the heart a tune-up for 1 year or 30 million beats, whichever comes first (Chest)
• Obstructive sleep apnea increases risk for postop complications (CHEST)
• Corticosteroids do indeed work for severe COPD exacerbations (RCT, Arch Intern Med)
• Knowing When, When Knowing Is Impossible (Paul McLean)
• How to make $25,000 on each EBUS (Chest)
• Got sleep apnea? Climbing Everest? Pack your Diamox (RCT, JAMA)
• Omega-3 fatty acids for acute lung injury/ARDS are useless-to-harmful (OMEGA RCT, JAMA)
• In undiagnosed COPD, lower FEV1/FVC predicts lung function decline, death (AJRCCM)
• 13 doses rifapentine + isoniazid as good as 9 months INH for latent TB (RCT, NEJM)
• Blood pressure cuffs reliable for identifying hypotensive patients (Crit Care Med)
• Linezolid not better than vanco against MRSA pneumonia in 3rd meta-analysis (CHEST)
• Procalcitonin to guide (reduce) antibiotic use: meta-analysis, reviews
• Idiopathic pulmonary fibrosis: Tyrosine kinase inhibitor BIBF 1120 appeared helpful (RCT, NEJM)
• Chest X-ray useless for lung cancer screening? (PLCO Trial, JAMA)
• NYU’s Clinical Correlations: a great internal medicine review
• Talking to COPD patients about end-of-life makes them like you more (Chest)
• Should you check pleural manometry during thoracentesis? (Pro/Con, Chest)
• Chantix: no excess cardiovascular risk in new meta-analysis (BMJ)
• Westermark sign in pulmonary embolism (Image, NEJM)
• COPD self-care program fail; unexplained deaths at VA hospitals (RCT, Ann Intern Med)
• Restrictive blood transfusion was fine for high-CV-risk patients after hip fracture repair (RCT, NEJM)
• Linezolid (Zyvox) good for MDR, XDR tuberculosis (RCT, NEJM)
• Severe refractory asthma: International consensus statement (Thorax Review, Guideline)
• Big bucks riding on FDA’s little dosing decision for indacaterol (NEJM)
• How to bill for palliative care in the ICU … legally (Chest)
• GM-CSF (Leukine) for acute lung injury & ARDS (RCT, Crit Care Med)
• New pleural mesothelioma biomarker can speed diagnosis (NEJM)
• Reslizumab improved lung function in severe asthmatics (RCT, AJRCCM)
• GSK’s new once-daily inhaled fluticasone product worked in Phase 2 trial (RCT, Thorax)
• Refractory asthma: Bronchoscopy may guide effective therapy (CHEST)
• No difference in outcomes with early vs late TPN in observational trial (Crit Care Med)
• COPD heterogeneity: FEV1 decline varies widely (AJRCCM)
• Dalteparin vs. unfractionated heparin for ICU DVT prophylaxis (PROTECT Trial, NEJM)
• Barium swallow fail kills patient (Image, NEJM)
• Joint Commission launches new smoking cessation performance measures (NEJM)
• Thoracic ultrasonography: benefits abound; resistance is futile (Review, CHEST)
• Insurers sound off to NPR against moneymaking sleep centers
• Obesity may improve survival in ARDS, but with renal failure (Crit Care Med)
• Hypertonic saline for stroke with cerebral edema
• I.V. beta-agonists for ARDS harmed people; BALTI-2 stopped early (RCT, Lancet)
• Help PulmCCM Get to the Next Level in 2013: Invest Today!
• Asthma update: What we know we don’t know (is a lot) (Review, J Allergy Clin Immunol)
• Hospital-acquired infections: stopping Gov’t payment did not reduce their incidence (NEJM)
• To grade severity of mixed restrictive/obstructive disease, just divide FEV1% by TLC%, authors propose (CHEST)
• It’s official — Someone’s being too negative (Crit Care Med)
• What we know about lung volume reduction surgery, thanks to NETT (Review, AJRCCM)
• Tattletales rain on private cardiologists’ cash-grabbing parade (JAMA)
• Rate of early lactate clearance predicts survival in ICU (Critical Care)
• Deep sulcus sign in pneumothorax (Image, NEJM)
• The net from NETT: What we’ve learned of COPD, ten years later (Review, AJRCCM)
• Is half of current medical practice just plain wrong? (Essay, JAMA)
• National Lung Cancer Screening Trial results (RCT, NEJM)
• Could excess ICU beds be hazardous to your health? (Chest)
• Elderly critically ill who survive ICU rationing live well (CHEST)
• CHEST retracts “Chest Tubes for Transudative Effusions” for “incorrect data”
• Heads of beds in ICU? Use your own head, guideline critiquers say
• In idiopathic pulmonary fibrosis, is an FVC change of 2-6% clinically significant? (AJRCCM)
• Cochrane review on roflumilast and cilomilast
• Watch out for staph coinfections in severe influenza pneumonia (MMWR)
• PulmCCM App for iPhone Launches! (Again)
• Pertussis underdiagnosed; adult booster-vaccine prevents “whoop” & infant deaths (NEJM Video)
• For some LTAC patients, pessimism is the new kindness (Crit Care Med)
• N-acetylcysteine alone doesn’t prevent contrast nephropathy after angiography (RCT, Circulation)
• How to cure abdominal compartment syndrome without surgery (CHEST)
• Taking Apixaban (Eliquis) after completing Coumadin prevents recurrent DVT/PE (NEJM)
• Dynamic extrathoracic airway obstruction (NEJM Video)
• In COPD, vitamin D deficiency is predictive of … nothing (AJRCCM)
• Procalcitonin algorithm led to slightly worse outcomes (RCT, Crit Care Med)
• More are surviving severe sepsis … to go to LTACs (CHEST)
• LTAC transfers are creating biased, gamed hospital-stay stats (AJRCCM)
• CPAP worked for the sleepy with mild-moderate OSA (RCT, AJRCCM)
• Most oncologists dump end-of-life talks on other MDs (Ann Intern Med)
• Evidence supporting CAP performance measures is weak
• Death or disability in 84% of Medicare beneficiaries 1 yr after mechanical ventilation (AJRCCM)
• Statins for acute lung injury? (HARP trial, AJRCCM)
• Tranexamic acid for intracranial hemorrhage (CRASH-2 trial)
• Withhold CPR from some patients, Harvardians advise. OK — you go first! (JAMA)
• Acetaminophen causes childhood asthma, researcher argues (Pediatrics)
• Vitamin D is for “doesn’t do diddly” for the common cold (RCT, JAMA)
• Fresh blood vs. stale: No detectable difference (RCT, AJRCCM)
• Toxicology in the ICU Part 1: General Overview and Approach to Treatment (CHEST Review)
• A New Way to Share: PulmCCM on Doximity
• Subglottic drainage of secretions reduces VAP (Meta-analysis; Review)
• Voice of sanity: Reduce medical training by at least 2 years (JAMA)
• Do oral beta-blockers really exacerbate asthma?
• Rituximab improved pulmonary alveolar proteinosis in pilot study (Eur Resp J)
• Bioengineered tracheas successfully transplanted in two men (Lancet, NYT)
• Nicotine patches don’t help in pregnancy, esp. if you don’t wear them (RCT, NEJM)
• Bronchoalveolar lavage’s role in diagnosis, management of interstitial lung disease (Review, Eur Resp J)
• Pair of lungs found on L.A. sidewalk
• Blood banks recommend restrictive transfusions in ward patients (Ann Intern Med)
• Cage Match! Tiotropium vs. Salmeterol in time-to-COPD exacerbation (POET-COPD trial, NEJM)
• Last Week To Help PulmCCM on Indiegogo
• Automatic ET-tube cuff pressure-minder prevents microaspiration, VAP (RCT, AJRCCM)
• Apixaban for thromboprophylaxis post-discharge causes bleeding (ADOPT Trial, NEJM)
• Triple inhaler therapy for COPD? (Cochrane review)
• Procalcitonin and CRP as pneumonia biomarkers
• Five-year outcomes after ARDS (NEJM)
• New molecular test predicts lung cancer survival better than staging (Lancet)
• Using central venous oxygenation to guide therapy for sepsis & others (AJRCCM Review)
• Empiric antibiotics for HCAP/VAP were appropriate – yet deadly? (Lancet ID)
• Omitting heparin prophylaxis in first 24 ICU hours associated with higher mortality (CHEST)
• PulmCCM App Is Back Online
• Fosfomycin/tobramycin: inhaled combo preserved lung function in cystic fibrosis (RCT, AJRCCM)
• Beta-agonist therapy unhelpful for ALI / ARDS (RCT, AJRCCM)
• Delaying total parenteral nutrition improved outcomes (RCT, NEJM)
• Semuloparin (a new LMWH) reduced DVT & PE in chemotherapy patients (RCT, NEJM)
• It’s the drugs, not the bugs, that determine survival in sepsis (but you already knew that)
• Pulmonary thrombosis/PE in 17% of sickle cell pts w/ acute chest syndrome (AJRCCM)
• Update in Mechanical Ventilation 2010. (Review)
• TGIF: Intensivists’ weekends off don’t hurt patients, but do prevent burnout (RCT, AJRCCM)
• Hypothermia looks unhelpful for out-of-hospital PEA/asystole (Circulation)
• Weaning protocols for mechanical ventilation: review
• Release the data on Relenza and Tamiflu, Cochrane implores Pharma (NYT)
• Proposed cut-off for harmless parapneumonic effusion: 2.5 cm on CT (Eur Resp J)
• Corticosteroids for ARDS from H1N1 influenza
• Adaptive support ventilation weaned COPD patients faster than pressure support (RCT, Eur Resp J)
• Severe asthma NHLBI update: Your tax dollars at work (Review, AJRCCM)
• Targeted temperature management in critical care: Recs from 5 professional societies. (Review, Crit Care Med)
• Lansoprazole didn’t help kids with uncontrolled asthma (RCT, JAMA)
• Most primary care MDs order lung cancer screening on asymptomatic smokers
• Coronary artery disease makes COPD symptoms worse (CHEST)
• Vitamin D supplements don’t prevent COPD exacerbations in RCT (Ann Intern Med)
• AMA helps “data miners” make billions off your personal info. Want to opt out?
• Most clinical trials are too small, often underpowered (JAMA)
• Sildenafil appears safe, effective for long-term PAH treatment (SUPER-2, CHEST)
• Big Tobacco win: Feds to take breather in fight for scary cigarette labeling
• COPD: Exhale airway stents didn’t help (bronchoscopic lung-volume reduction EASE trial – RCT, Lancet)
• Inhaled hypertonic saline for young kids with cystic fibrosis: no benefit? (RCT, JAMA)
• Indacaterol vs. tiotropium for once-daily COPD Rx (RCT, Eur Resp J)
• High-concentration oxygen caused hypoventilation in asthma exacerbation pts (RCT, Thorax)
• In COPD patients with pneumonia, prior use of inhaled corticosteroids strongly associated with better outcomes (VERDICT program)
• Thin elderly with mild COPD at highest risk for lung cancer (AJRCCM)
• Ventilation strategy using low tidal volumes, recruitment maneuvers, and high PEEP for ARDS/ALI (RCT)
• Most people admitted to U.S. ICUs are not that sick (Review, CHEST)
• Chronic thromboembolic pulmonary hypertension (Review, AJRCCM)
• Grow your own new lungs — just add some (newly discovered) stem cells!
• ECHO was inaccurate for pulmonary artery pressure, compared to right heart cath
• Texting resident fails to stop warfarin; hemopericardium ensues
• Do you have cooties? MDR-bug transmission rates in ICUs (Crit Care Med)
• Pressors and inotropes in circulatory shock (Review)
• Palliative care exploding in U.S. hospitals (AP)
• VAP mortality = 1%, newfangled research methodology concludes (AJRCCM)
• Current Controversies and Future Perspectives in Chronic Obstructive Pulmonary Disease (AJRCCM Review)
• No increased risk detected from smoking cessation just before surgery (Arch Intern Med)
• ECMO rising? Looks like it saved lives in H1N1 pandemic (JAMA)
• Organ failure in the ICU (Special Issue, Semin Resp Crit Care Med)
• Sleepy cops abound; you won’t like them when they’re angry (JAMA, NYT)
• An overdue vacation …
• Chantix users reported thousands of suicidal thoughts and self-harm (Review, PLoS One)
• 6 minute walk test; 60 minutes to interpret results? (Review, AJRCCM)
• Ventilator-associated tracheobronchitis, or VAP? (CHEST)
• Intensive glucose control in kids: no brain injury vs. standard care 3 yrs later (RCT, JAMA)
• You think you’ve got it rough? German docs make $60K, strike (Lancet)
• Novel therapies for septic shock over the past 4 decades. (Review, JAMA)
• Kick your patients (gently) till they kick the habit (Review, NEJM)
• Ivacaftor, a CFTR potentiator, improved lung function in certain cystic fibrosis patients (RCT, NEJM)
• For most, plane flights add no DVT/PE risk (just stretch your legs)
• Talc pleurodesis safe for primary spontaneous pneumothorax, authors say (Eur Resp J)
• Asthma and genes: Polymorphism discovered that may cause steroid resistance (NEJM)
• Does incentive spirometry actually work?
• Lebrikizumab, an IL-13 inhibitor for asthma, improved lung function but not clinical outcomes (NEJM, RCT)
• Obstructive sleep apnea not associated with hypertension in community cohort (AJRCCM)
• Cough leads to lung herniation through chest wall (Image, NEJM)
• Lack of ICU beds has no effect on mortality … in Canada? (Arch Intern Med)
• Chronic Cough: Controversies in evaluation and management (Review, AJRCCM)
• Ultrasound reduced complications of subclavian central line placement
• Noninvasive ventilation for weaning after failed SBT didn’t prevent reintubation in VENISE trial (RCT, AJRCCM)
• Current Approach to the Diagnosis of Acute Nonmassive Pulmonary Embolism (Review, CHEST)
• Catheter-based reperfusion in pulmonary embolism (Review, Circulation)
• Severe sepsis is immune-suppressing, organ harvest reveals (JAMA)
• Clinical decision rules for PE coagulate into meta-mishmash (Ann Intern Med)
• Pro/Con debate on mild hypothermia after out-of-hospital cardiac arrest (BMJ)
• Epinephrine in field no help after out-of-hospital cardiac arrest? (JAMA)
• Most with ALS getting tracheotomy live longer than 1 year (Thorax)
• Smoking is bad, quitting is good — even for Great-Grandma (Arch Intern Med)
• Meds often stopped after ICU stays: deaths result? (JAMA)
• The reaper rarely phones ahead: Mortality prediction tools good, not great (Review, Arch Intern Med)
• Hypertonic saline vs. mannitol for elevated ICP, meta-analysis
• Sarcoidosis, Interstitial Lung Disease, Pulmonary Vascular Disease (Special Issue, Review)
• Delirium in the ICU, management of (Review)
• Tiotropium improved FEV1, but not symptoms, in severe asthma (RCT)
• Phase III trials for aclidinium, a “me-too” antimuscarinic, in COPD (ACCLAIM I & II)
• Where’s the respect (and $$) for critical care research? (Crit Care Med)
• Defining COPD exacerbations by questionnaire
• Obesity Hypoventilation Syndrome (Review, AJRCCM)
• Surprise: Bronchoconstriction (not just inflammation) causes airway remodeling in asthma (NEJM)
• New scoring system predicts 1-year chance of death from idiopathic pulmonary fibrosis
• Pulmonary cement embolism caused by vertebroplasty (Image, NEJM)
• In idiopathic pulmonary fibrosis, maybe we “do something” after all (AJRCCM)
• “First dibs” on patients by sleep docs increased CPAP adherence (CHEST)
• PET-CT’s high rate of false-positive mediastinal nodes wrongly excludes patients from curative surgery for NSCLC
• Chest tubes for transudative effusions in vented patients? Show us the data!
• Hypertrophic pulmonary osteoarthropathy with tripe palms (Image, NEJM)
• PE incidence after knee surgery: 0.27% with prophylaxis (Meta-analysis, JAMA)
• Overdiagnosis of PEs on CT-angiograms seems likely (Ann Intern Med)
• Atelectasis causes post-op fever? Doubtful.
• Lay press eats helping of hype on sleep apnea & “silent strokes”
• Upper limit of normal for pulmonary artery pressure = 40 for endurance athletes?
• Lung transplantation. (Review)
• U.S. Gov’t purse strings may be tightening on GME programs (NEJM)
• Lung cancer screening with chest CT: Pro/Con (Ann Intern Med)
• End-stage liver disease, critical care management of (Review)
• Don’t text-and-doctor, authorities warn (NYT)
• Physician identity theft on the rise; who knows your Medicare number? (JAMA)
• Nebulized Gentamicin Helped non-CF Bronchiectasis Patients
• Prompters’ prompting prevented problems, permitted pulling patients’ ET tubes promptly (AJRCCM)
• Black lung resurges in Appalachian coal country; mining co’s not penalized (Ctr for Public Integrity)
• Montelukast improved peak flow during acute asthma exacerbations (RCT, Thorax)
• The pleura and pleural diseases (Special Issue)
• Cytisine, a cheap seed extract, helped smokers quit (RCT, NEJM)
• Sarcoidosis; Interstitial lung disease; Pulmonary embolism (Special Issue, Review, Curr Opin Pulm Med)
• Mediastinal lymphadenopathy common in severe CHF?
• Cochrane to Pharma: stop hiding data on Relenza and Tamiflu
• Reslizumab (IL-5 inhibitor) improved FEV1, but not outcomes in eosinophilic asthma (RCT, AJRCCM)
• Think NIPPV overnight is useless for stable hypercapneic COPD? TURN IT UP, MAN! (CHEST)
• Tension pneumothorax or tension bulla? (Image, NEJM)
• Proning plus recruitment improved oxygenation in ARDS
• Salt, water, edema, CHF contribute to obstructive sleep apnea (AJRCCM, JACC)
• Inoculating pleural fluid into blood culture bottles improved yield in empyema
• Clinical Course & Prediction of Survival in Idiopathic Pulmonary Fibrosis (Review)
• Intracerebral hemorrhage, acute management of (Review)
• Chronic thromboembolic pulmonary hypertension registry reveals new insights (Circulation)
• Optimal duration of anticoagulation after VTE (Review, Circulation)
• Effects of asthma treatment on airway remodeling (J Clin All Immunol Review)
• FDA: Chantix not associated with psychiatric hospitalizations
• Acute lung injury & critical care update for 2010 (Review)
• Long-term complications of critical care (Review)
• For Pseudomonas VAPs, nebulized ceftazidime + amikacin was as effective as I.V.
• Regular nagging + nicotine better than benign neglect for smoking cessation (RCT, Arch Intern Med)
• Cost shifting of asthma meds to patients had little effect on adherence, outcomes (JAMA)
• Bizarre vendetta against e-cigarettes by public health authorities may harm smokers (NYT)
• Chest CT and non-PFT clinical data can detect undiagnosed COPD. But should they? (JAMA)
• AHA Scientific Statement on Management of VTE Badness (Review, Circulation)
• Ventilation with lower tidal volumes as compared with traditional tidal volumes for ALI and ARDS
• More lungs, please! Ex-vivo lung perfusion might convert bad donor lungs to good (NEJM)
• People with asthma perceive snake oil to work as well as albuterol (RCT, NEJM)
• Nutrition + weights + testosterone improved function in chronic respiratory failure (RCT, Thorax)
• DVT/PE in the ICU: Prevention (more heparin) beats screening (ultrasound) in cost-effectiveness model (AJRCCM)
• Contrast nephropathy prevented by RenalGuard’s extra saline and furosemide (RCT, Circulation)
• Patients’ Families Unmoved by End-of-Life Care Intervention Bundle (RCT, AJRCCM)
• FACTT post-hoc: Transfusion might cure, kill or both during shock & acute lung injury…who knows? (Crit Care)
• Subarachnoid hemorrhage, critical care of (Review)
• Beta-blockers associated with improved survival in COPD
• Managing cystic fibrosis: strategies that increase life expectancy and improve quality of life. (Review)
• Nicardipine beat labetalol in hypertensive emergency
• Septic shock: Beta-lactam levels unpredictable, need close monitoring (Review, Crit Care)
• EBUS good at diagnosing TB in thoracic lymph nodes (Thorax)
• Home testing is sensitive in severe, but not mild-to-moderate obstructive sleep apnea (RCT, AJRCCM)
• VAP prevention through GI/respiratory decontamination (meta-analysis)
• CT scans! Get your lung cancer-curing CT scans here — only $99.95!
• Beware the Ides of July: Interns don’t kill people, changeover does (Review, Ann Intern Med)
• Adaptive ventilation improved complex sleep apnea in CHF patients
• Outpatient treatment for pulmonary embolism
• Survival of trauma patients after massive red blood cell transfusion using a high or low red blood cell to plasma transfusion ratio. (Review)
• Risk of complications after transthoracic needle biopsy: population analysis
• Acute liver failure (Review)
• Update on Pulmonary Vascular Diseases 2010. (Review)
• Pulmonary Sarcoidosis: Concise Clinical Review.
• NSCLC: Use of biomarkers in prognosis, treatment (Review, J Thorac Oncol)
• Update in cystic fibrosis 2010. (Review)
• Cryptogenic and secondary organizing pneumonia (Review)
• PulmCCM’s new & improved search engine: now with Google
• Trophic vs full-calorie enteric feedings for ventilated patients (RCT, NEJM)
• Sirolimus was helpful for LAM, but with toxicity (RCT, NEJM)
• African-Americans’ asthma milder at baseline, but more prone to treatment failure (AJRCCM)
• Early vs. late percutaneous tracheotomy after cardiac surgery (Ann Intern Med)
• PET-CT’s diagnostic accuracy plummets in region endemic for granulomatous disease (southeast U.S.)
• Risk of death associated with mechanical ventilation between 1 and 7 days … all about equal?
• Makin’ a list, checkin’ it twice, to see how much $$ docs take from pharma (NYT)
• How to reduce asthma exacerbations (Asthma Review)
• Lancet called; they want to make you famous
• Critical care for patients with stroke (Review)
• EBUS FNA very good at finding lymph node mets from extrathoracic malignancy (J Thorac Oncol)
• Respiratory Viral Infections (Special Issue, Review)
• Probiotics may prevent colds (Cochrane review)
• Number of positive lymph nodes predicts survival in N1 non-small cell lung cancer
• Obstructive Sleep Apnea: An Emerging Risk Factor for Atherosclerosis (Review)
• Update in Tuberculosis and Nontuberculous Mycobacterial Disease 2010. (Review)
• Do the Brits have an ICU bouncer?
• Pulmonary rehab results in skeletal muscle remodeling in mild as well as severe COPD (CHEST)
• GOLD spirometry criteria overdiagnosed COPD
• Asthma in pregnancy: Using exhaled nitric oxide can aid management (RCT, Lancet)
• Even extreme obesity doesn’t reduce survival in critical illness (CHEST)
• Emergencies (initial management); postoperative problems (Special Issue, Review)
• With OSA, stopping CPAP makes you sleepy, snorey, sicker … and studyable! (RCT, AJRCCM)
• Cystic fibrosis patients could inhale dornase alpha anytime, evidence says
• Ultrasound vs. chest X-ray for dyspnea in the ER
• COPD in never-smokers: BOLD unravels some of the mystery
• Pharma to launch 5 large trials on LABA safety for asthma
• Combining PET and volume-doubling time could improve lung nodule management
• Update in Asthma 2010 (Review)
• What’s the best long-term anticoagulation Rx after a stent for people needing warfarin?
• Lung vasculitis and alveolar hemorrhage. (Special Issue, Review)
• Trouble sleeping? Don’t read this, it’ll only make it worse (Circulation)
• Rapid tests for aspergillus in BAL
• Lung transplantation. (Special Issue, Review)
• Prior broad spectrum antibiotics associated with deadlier Gram-negative sepsis
• Bronchiolitis Obliterans Syndrome: The Final Frontier for Lung Transplantation (Review)
• Tobacco warnings, free speech, and “in-activist” judges (NEJM)
• Where’s the money in health reform – and WTH is an ACO anyway? (KevinMD)
• Pneumopericardium Associated with a Peptic Ulcer (Image, NEJM)
• In TB + HIV, starting antiretrovirals earlier saved lives (CAMELIA RCT, NEJM)
• Diffuse parenchymal lung disease, Update for 2010 (Review)
• DVT of the upper extremity (Review)
• Doctors easily fooled by bright, shiny statistics (Ann Intern Med)
• Chantix and cardiovascular risk: meta-analysis (CMAJ)
• Pulmonary artery pressure measurement by echocardiography
• No, you can’t use the femoral vein line for central venous saturations.
• MRSA & VRE in the ICU: Heightened surveillance and barrier precautions didn’t reduce transmission (STAR*ICU trial)
• Six-minute walk test is useful in the sickest IPF patients
• Xolair for inner-city kids with asthma (ICATA Trial, NEJM))
• In people with coronary artery disease, is fat a friend or foe? (RCT, CHEST)
• Aerosolized levofloxacin for CF patients with chronic Pseudomonas
• Follow-up and nonpharmacological management of the idiopathic pulmonary fibrosis patient. (Review)
• Oral / gastric antibiotic decontamination reduced bacteremias in ICU
• Fidaxomicin cures C.diff infections like vancomycin; prevents more recurrences (RCT, NEJM)
• Predicing vancomycin failure in MRSA bacteremia
• Diuretics in acute decompensated CHF
• Pulmonary rehabilitation, realities in clinical practice. (Review)
• “82 … 82 … 82 …” COPD’s airflow limitation caused by loss of airways, not emphysema, say counters (NEJM)
• Pleural effusions more common in PAH than believed?
• Occupational organic dusts assoc w. increased lung cancer risk (Thorax)
• Leukotriene antagonists as good as inhalers for asthma? (RCT, NEJM)
• Outcomes after tunneled pleural catheters for malignant effusions
• Omega-3 fish oils in acute lung injury had no effect (RCT, Crit Care Med)
• Sirolimus improved chylous pleural effusions, lung function in LAM
• Antibiotic dosing in multiple organ dysfunction syndrome (Review)
• Accountability for Medical Error: Moving Beyond Blame to Advocacy (Review)
• Acute-on-chronic liver failure, concept, natural history, prognosis (Review)
• Oral contraceptives with drospirenone increase risk of nonfatal DVT/PE (BMJ)
• Glycemic Control in the ICU. Review
• Heparin-induced thrombocytopenia in the ICU (Review)
• “Changing the Course of COPD”: Proceedings of the ATS (Special Issue, Review)
• Rapid response teams. (Review)
• Tiotropium mist (Respimat) increases mortality risk, authors say
• Long-term Course and Prognosis of Idiopathic Pulmonary Fibrosis in the New Millennium
• For most with OHS, ventilatory drive was oxygen-sensitive (RCT, CHEST)
• Wait, 24/7 intensivist coverage is cheaper?
• COPD exacerbations worsen radiographic emphysema on CT
• A noninvasive test of respiratory work in COPD exacerbations that might be helpful
• Obesity raises risk of primary graft dysfunction after lung transplant (AJRCCM)
• An Official American Thoracic Society Statement: Work-Exacerbated Asthma (Guideline, Review)
• Hyperoxia after cardiac arrest maybe not so bad
• Non-CPAP therapies in obstructive sleep apnea (Review)
• Cystic fibrosis patients’ nebulizer adherence under 40%
• Outcomes after pulmonary metastasectomy: not too shabby (J Thoracic Oncol)
• ARDS with multi-organ failure … and more (Reviews)
• Predictors of mortality in pulmonary arterial hypertension
• PE diagnosis: “Thromboview” a novel alternative to CT-angiography (AJRCCM)
• Long-term outcome and mortality of obesity hypoventilation syndrome
• Probiotics and lung diseases (Review)
• Self-tapering of oral steroids in severe asthma
• Finding PET-CT’s place in mediastinal staging of NSCLC
• Lifetime risk of COPD is 28% in cohort study of 13M people (Lancet)
• Transfusing freshest RBC associated with better ICU survival
• Dexamethasone for community-acquired pneumonia?
• Status epilepticus, refractory, treatment of (Review)
• Inhaled denufusol for early CF
• Potential metabolic consequences of statins in sepsis. (Review)
• Gabapentin enacarbil for restless legs syndrome (PIVOT RLS II trial)
• New non-small cell lung cancer classification system
• Corticosteroids in community-acquired pneumonia
• Those with symptoms after breathing 9/11 dust more likely to have abnormal lung function (case-control, AJRCCM)
• ICU telemedicine shows improvements in survival, other quality outcomes (finally)
• Update in Pulmonary Infections 2010. (Review)
• Survivor after critical illness shares her story
• New treatments against gram-negative organisms. (Review)
• Beclomethasone as rescue-therapy-only for childhood asthma
• Use of CPAP reduces triglycerides and total cholesterol in OSA (RCT)
• Interobserver variability in applying a radiographic definition for ARDS
• Reduced poverty = reduced obesity and diabetes (RCT, NEJM)
• Employers charging smokers more for medical care insurance (NYT)
• Citing COI, IOM issues guidelines for new guidelines (JAMA)
• Hyperbaric oxygen in the critically ill.
• Bone Marrow-Derived Stem Cells and Respiratory Disease. (Review)
• Once-daily indacaterol as effective as salmeterol bid for COPD
• Lymphangioleiomyomatosis. (Review)
• Outcomes after ARDS
• Creepy … MRSA’s “MIC creep” to vancomycin portends worse outcomes
• Code status & patient expectations — reality disconnect
• Clinical risks for development of ARDS
• V/Q, ultrasound in lieu of CT-angiography for diagnosis of PE
• Serious Infections in Intensive Care Units: 100+ pages, 12 articles reflecting the state of the art on managing infections and antibotic usage in the ICU (Special Issue)
• Nesiritide for decompensated CHF goes under the bus
• Natural history of nonspecific pulmonary function tests
• Pseudomonas pneumonia part II, antibiotic therapy, resistance, pharmacodynamics (part 2 of 2 Review)
• Update on tuberculosis: TB in the early 21st century. (Review)
• Pro/Con debate: Measuring sputum eosinophils in severe asthma
• Workshop on molecular diagnostics for respiratory tract infections (Special Issue)
• Pulmonary alveolar proteinosis. (Review)
• Reversed Halo Sign (Image)
• Does CT-guided needle biopsy seed the pleura with cancer?
• Potential new biomarker for COPD?
• Too old for lung resection for NSCLC? In France, the answer is “Non!” (CHEST)
• Long-term oxygen therapy (Review)
• Diseases of the pleura, and neoplasms of the lung (Special issue, review)
• Data sketchy on prolonged antibiotics for bronchiectasis
• People with COPD at higher risk for bad outcomes 1 year after stenting for CAD (CHEST)
• Nebulized hypertonic saline reduces inflammation in CF bronchi
• In COPD, there are the quick — and the dead
• Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome
• Has the biomedical research-industrial complex lost its way?
• Pulmonary Complications of Lung Transplantation (Review)
• Update in Lung Cancer and Oncological Disorders 2010 (Review)
• Another new TB test (“MODS”) superior to smear microscopy
• What the pulmonary specialist should know about the new inhalation therapies. (Review)
• How many people with DVT / PE already have HIT antibodies at presentation? (And should we care?)
• Fixed-dose drug combination non-inferior to loose pills for tuberculosis
• Vitamin D deficiency associated with mortality in critically ill
• Bad livin’ is protective, sort of … mortality from 1st MI inversely related to risk factors (JAMA)
• Antimicrobial Stewardship for the Community Hospital: Practical Tools & Techniques for Implementation. (Special Issue, Review)
• In cystic fibrosis, more exacerbations worsen outcomes in adults (just like kids)
• Oxygen sensing, homeostasis, and disease (Review)
• Toward a better diagnosis of idiopathic pulmonary fibrosis. (Review)
• Toxic epidermal necrolysis and Stevens-Johnson syndrome. (Review)
• Apixaban better than aspirin for atrial fib
• Anticholinergic inhalers associated with slightly increased risk for acute urinary retention
• Autofluorescence vs white light bronchoscopy to diagnose lung cancer (meta-analysis, review)
• Death panelists unite! Advance directives restrain high-billing MDs (JAMA)
• Is your stage III NSCLC patient truly “downstaged” to N0? EUS helpful only if positive (J Thorac Oncol)
• A brief historical and theoretical perspective on patient autonomy and medical decision making: Part II: the autonomy model. (Review)
• Acute exacerbations of IPF portend grim outcome
• Indacaterol’s benefit keeps going at least through year 1
• Year in Review 2010 in pulmonary & critical care (Review)
• Association Between Time of Admission to the ICU and Mortality: A Systematic Review and Meta-analysis
• A little longitudinal data on the enigmatic “complex sleep apnea”
• Inspiratory muscle training liberated the hard-to-wean
• Vardenafil says “me too” for PAH
• Ciclesonide tests its “me too” claim vs Advair for asthma
• Airway remodeling and its relationship to inflammation in cystic fibrosis. (Review)
• Lung Transplant Patients with RSV: Inhaled RNA Prevents BO?
• One-year outcomes in survivors of the acute respiratory distress syndrome
• Post cardiac arrest syndrome: Review of therapies
• During lung transplant for IPF, high pulmonary artery pressure predicted graft failure
• Get more sleep — it’ll improve your jump shot (Sleep)
• Feds at HHS release final regulations for ACOs (NEJM)
• CPAP for OSA after stroke improved neuro outcome, reduced cardiovascular risk
• Smells like victory! Diesel fumes implicated as likely cause of lung cancer
• Lung cancer diagnosis and treatment: summary of updated NICE guidance. (Review)
• Impedance threshold device during CPR didn’t improve outcomes after out-of-hospital cardiac arrest (RCT, NEJM)
• Improving survival after out-of-hospital cardiac arrest: AHA Consensus Statement. (Review)
• Is polysomnography unnecessary for diagnosis of OSA?
• Uninsured critically ill less likely to get essential care, survive (AJRCCM)
• Point-of-care ultrasonography (Review)
• Minimal physical therapy didn’t improve outcomes post-ICU
• Pseudomonas pneumonia: Epidemiology, clinical diagnosis, source (Part 1 of 2 part review)
• Viral community-acquired pneumonia (Review)
• Sickle cell patients need right heart cath, not echo, to diagnose pulmonary hypertension (like everyone else)
• Fresh frozen plasma transfusion practices: anarchy in the UK
• Kids who sleep less get fatter? (FLAME study)
• Annual Review of Advances in Non-small Cell Lung Cancer Research: A Report for the Year 2010 (Review)
• Home testing & CPAP titration was fine for most vets with OSA
• Tako-tsubo cardiomyopathy, natural history of (Review)
• Nocturnal monitoring of home non-invasive ventilation (Review)
• Nasal and full-face CPAP masks generally equivalent for OSA treatment
• Texting helped smokers quit (txt2stop trial)
• Update in sleep medicine 2010. (Review)
• Hydrocortisone in multiple trauma (HYPOLYTE trial)
• Sleep-disordered breathing predicted future cognitive dysfunction in older women
• From intensive care to critical care medicine: a historical perspective (Review)
• Asthmatics’ vocal cord movement frequently abnormal on experimental CT imaging
• Transtracheal oxygen therapy (Review)
• Sleep apnea in CHF may be dangerously underdiagnosed
• Progressive massive fibrosis in coal miners on the rise
• Molecular diagnosis of respiratory tract infection in COPD exacerbations (Review)
• Autonomy and beneficence, a historical perspective (Review)
• Wrist actigraphy (Review)
• Dabigatran, a new oral thrombin inhibitor (Review)
• VAs nationwide report success of an MRSA bundle (NEJM)
• COPD Update for 2010 (Review)
• Parapneumonic effusions, empyema doubled in U.S. over past decade
• In out-of-hospital cardiac arrest, interrupting CPR after 30 sec, 1 or 3 minutes before checking rhythm made no difference (RCT, NEJM)
• Acute lung injury not improved by recombinant surfactant protein C product
• Parasitic infections of the lung: a guide for the respiratory physician. (Review)
• The Research Agenda in ICU Telemedicine: A Statement From the Critical Care Societies Collaborative. (Review)
• Biomarker for early COPD could “scare straight” smokers?
• Clinical decision rules for PE prospectively validated … or were they? (Promethus study)
• Mucormycosis: clinical presentations and management (Review)
• Inspiratory muscle training in COPD (Review)
• Circulating fibrocytes: potential biomarker for BOS after lung transplant?
• Percent positive of sampled lymph nodes predicts prognosis in N1 NSCLC
• Obesity associated with increased risk of severe seasonal influenza (not just H1N1)
• Fine-toothed comb blames inhaled steroids for TB
• Alveolar capillary dysplasia. (Review)
• UK investigators call entire concept of HCAP “controversial”
• Combating antimicrobial resistance; Policy recommendations to save lives (Special Issue)
• Treating NSCLC with tyrosine kinase / EGFR inhibitors erlotinib & gefitinib (Review)
• Lung cancer in COPD: enhancing surgical options and outcomes (Review)
• 1 in 5 idiopathic pulmonary arterial hypertension patients have >2 year delay in diagnosis
• Cardiopulmonary arrest and cardiopulmonary monitoring. (Special Issue, Review)
• Heroes come home from Iraq, Afghanistan with constrictive bronchiolitis
• Quitting smoking heralds lung cancer?
• Antimicrobial “locking” of dialysis catheters prevented bloodstream infections
• No excess risk of severe pneumonia with inhaled steroids for COPD (case/cohort study)
• Pregnancy and respiratory disease (Special Issue)
• The utility of cardiopulmonary exercise testing in difficult asthma
• Mechanical ventilation safe for pigs, and people?
• Sleep disordered breathing plus daytime somnolence associated with early death in elderly
• Exhaled hydrogen peroxide a potential biomarker for asthma?
• Blood test for invasive fungal infections
• The slow death of empathy, or how we all became such jerks
• Millions of adults quit smoking since 2005 (MMWR)
• I learned it from watching YOU, Mum!! U.K. kids smoke more when parents, siblings do (Thorax)
• Moviegoing U.K. teens smoke more (Thorax)
• Chronic rhinosinusitis: oral steroid “priming” helped
• The effect of light on critical illness (Review)
• Activated protein C for severe sepsis: review
• Radiographic emphysema correlated with low bone mineral density
• Tuberous sclerosis with LAM can present in adults
• Many UK immigrants have undetected latent TB; IGRA could help
• Extent of lymph node dissection during lung ca resections
• Budesonide doesn’t cause pneumonia in asthmatics
• Long-term survival after carcinoid resection is excellent
• Biggest losers shed 22 pounds in Qnexa weight loss drug trial
• The new perpetual squeeze on physician reimbursements
• Recurrence risk after venous thromboembolism
• Pramipexole for restless legs syndrome
• Degree of overventilation during exercise predicts bad outcomes in heart failure (Review)
• Pertussis vaccine wanes even faster than thought?
• New H3N2 swine flu emerges, in isolated cases only (MMWR)
• Candida urinary tract infections (Review)
• CPET identified those with lung ca at high perioperative risk
• Etanercept ineffective for moderate-to-severe asthma
• Elevated mesenchymal cells in BAL predicts post-lung transplant BOS
• Patients on continuous renal replacement may need higher beta-lactam doses
• Team science and critical care. (Review)
• Computer model says vanco near useless, toxic for MRSA with MIC > 1.9
• Preloading with Chantix improved smoking cessation rates
• Most Taiwanese chronic critically ill live ~2-6 months on the vent
• Venous thromboembolism, long term management of (Review)
• Fundoplication for reflux associated with reduced allograft dysfunction
• Bupropion fails to improve smoking cessation post-heart attack
• Among Spain’s healthy elderly 12 months post-ICU, the half that survived lived well
• Docs don’t discuss end-of-life care preferences with patients in clinic
• Pro/con editorial on comparative-effectiveness research
• Osteopontin a possible biomarker for IPAH?
• Wedge resection looked OK for subcentimeter NSCLC, retrospectively
• Inactivity linked to pulmonary embolism risk
• Iron deficiency common in IPAH
• Smokers with abnormal screening CTs keep smoking
• Culture may miss most PCR-confirmed, often-resistant Aspergillus
• Single-center trials usually exaggerate effects: meta-analysis, review
• Do rapid response teams help?
• With declining prevalence of TB, screening provides diminishing returns (AJRCCM)
• Interferon-gamma release assays in the diagnosis of latent tuberculosis infection (Review)
• This is your brain on sleep apnea
• Patients unimpressed by flexible pressure CPAP
• No negatives observed from non-MDs in MICU
• Augmentation common during treatment for restless legs syndrome
• MTB/RIF test continues to trounce smear microscopy for tuberculosis diagnosis
• Health care 3.0 by Barry Coller
• Chantix worked in people with mild to moderate COPD
• How to lose friends and humiliate people
• Asthma, down on the farm (NEJM)
• Brain trust launches new CCM research database MIMIC II
• Educational intervention improved asthma control in adolescents
• On-site path improves transbronchial needle aspiration?
• Nonwhite patients got more aggressive ICU care at end of life
• Occupational asthma – Assessment, treatment, compensation (Review)
• Cardiopulmonary exercise testing in people with heart and lung disease (Review)
• Latent tuberculosis infection in the U.S. (Review)
• Why academic care isn’t the best care
• U.S. antibiotic-fed meat crawling with resistant S. aureus
• The new iUnit, by Apple?
• COPD is all in the family (or maybe just partly)
• Infectious complications typical after cardiac arrest
• The price of manners: $42 million (NYT)
• Viruses innocent in exacerbations of IPF?
• Those pesky poor people: Are they fueling the fires of burnout?
• Longitudinal studies of HIV-associated lung infections and complications in the era of antiretroviral therapy. (Special Issue, Review)
• And you thought Starbucks was expensive …
• Don’t exempt the mentally ill from smoking cessation efforts
• Obstructive sleep apnea didn’t depress cognitive function
• Sleep deprivation raised BP and orthostatic tendency in elderly
• ICU decedents’ families depressed, traumatized
• Sleep medicine training across the spectrum (Review)
• Low vitamin D common in asthmatic children
• Update in environmental and occupational medicine 2010. (Review)
• When after TB exposure does an interferon-gamma release assay become positive?
• CPAP adherence after home sleep testing was equal to in-lab PSG
• Survey says: Residents are sad, especially when they’re broke (JAMA)
• After COPD exacerbation, living in the woods was a risk factor for death
• The upper airways and nasal passages (Special Issue)
• NYC runs smokers out of public parks, beaches
• How industry stole the clinical trials game
• Thiazolidinediones probably increase risk for pneumonia, minimally
• New MTB/RIF test looks good for TB diagnosis
• Comprehensive intervention improved “safety climate” in ICUs
• Medicare wants health system change; puts $3.5B of GME’s funds at risk
• EBUS was good at differentiating new lung cancer from recurrence
• People with OSA have greater impairment in endothelial function after MI
• Sleep medicine, a 3,000-year history (Review)
• Diagnostic value of halo and reversed-halo signs in immune-compromised hosts. (Review)
• Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia. (Review)
• Poverty did not influence mortality after ICU stays
• Where the wild things are…
• Exercise associated with better asthma control
• Was it you?
• Double your pleasure, double your fun, double your radiation
• TBNA usually types NSCLC correctly
• No racial disparities seen in Cali ICUs
• Weight loss effectively treated OSA in men
• Cleaner air coming soon?
• Newports 1, U.S. public health 0
• Normal sleep in African-Americans and Caucasians (Review)
• Among Spain’s healthy elderly 12 months post-ICU, the half that survived lived well
• Give health delivery research some respect, yo
• Staph vaccine fails in cardiothoracic surgery patients (JAMA)