Review Articles Archives - Page 10 of 15 - PulmCCM
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Review Articles Articles

Sep 022011
 

September’s Current Opinion in Pulmonary Medicine has 4-5 review articles each on sarcoidosis (how to handle calcium problems; cardiac sarcoid); interstitial lung disease (biologics for connective-tissue disease related ILD; LAM therapies; stem cell therapy for pulmonary fibrosis), and pulmonary vascular disease. Curr Opin Pulm Med 2011;17.

Autofluorescence vs white light bronchoscopy to diagnose lung cancer (meta-analysis, review)

 Interventional Pulmonology, Lung Cancer, Review Articles  Comments Off on Autofluorescence vs white light bronchoscopy to diagnose lung cancer (meta-analysis, review)
Aug 292011
 

Sun et al pooled 21 studies (n=3,266) over 20 years. Autofluorescence added to traditional white light bronchoscopy appeared to possibly improve the sensitivity of detecting intraepithelial neoplasia, but not invasive lung cancer. J Thorac Oncol 2011;6(8):1336-1344. Review.

Antimicrobial Stewardship for the Community Hospital: Practical Tools & Techniques for Implementation. (Special Issue, Review)

 Critical Care, Infectious Disease and Sepsis, Review Articles  Comments Off on Antimicrobial Stewardship for the Community Hospital: Practical Tools & Techniques for Implementation. (Special Issue, Review)
Aug 272011
 

Antimicrobial Stewardship for the Community Hospital: Practical Tools & Techniques for Implementation. Clin Infect Dis 2011;53(suppl 1).

Subglottic drainage of secretions reduces VAP (Meta-analysis; Review)

 Critical Care, Mechanical Ventilation, Review Articles  Comments Off on Subglottic drainage of secretions reduces VAP (Meta-analysis; Review)
Aug 242011
 

Muscedere J. Subglottic secretion drainage for the prevention of ventilator-associated pneumonia: A systematic review and meta-analysis. Crit Care Med 2011;39:1985-1991. In short, it probably works to prevent ventilator-associated pneumonia (13 randomized trials, n=2,442. 12 were positive, pooled risk ratio 0.55, associated with 1-1.5 shorter days in the ICU and on the ventilator). So why not use [… read more]

How to reduce asthma exacerbations (Asthma Review)

 Asthma, Review Articles  Comments Off on How to reduce asthma exacerbations (Asthma Review)
Aug 232011
 

An excellent free full text review by Paul O’Byrne. What’s new here: Did you know that formoterol is used as a first-line rescue inhaler, outside the U.S.? Formoterol has a steeper dose-response curve than salmeterol: repeated doses have an additive bronchodilator effect. The use of budesonide/formoterol as a combination maintenance AND rescue inhaler (added prn [… read more]

Oxygen sensing, homeostasis, and disease (Review)

 Review Articles  Comments Off on Oxygen sensing, homeostasis, and disease (Review)
Aug 222011
 

Semenza GL. Oxygen sensing, homeostasis, and disease. NEJM 2011;365:537-547. An acronym-rich summary of decades of work by dozens of investigators eavesdropping on the secret messages cells send in response to hypoxia through HIF-1a, mTOR, VEGF and DMOG. I don’t understand a word of it, frankly. (Review)

Procalcitonin to guide (reduce) antibiotic use: meta-analysis, reviews

 Critical Care, Infectious Disease and Sepsis, Review Articles  Comments Off on Procalcitonin to guide (reduce) antibiotic use: meta-analysis, reviews
Aug 212011
 

Schuetz et al review the 16 randomized controlled trials (n=4,647) testing procalcitonin-guided vs. standard care on the outcomes of antibiotic use, mortality, and infection control. Most of these studies were done in Europe; 6 were in ICU patients. Using procalcitonin reduced antibiotic use in all settings (primary care, emergency department, ICU) with no detectable differences [… read more]

Accountability for Medical Error: Moving Beyond Blame to Advocacy (Review)

 Policy, Ethics, Education, Review Articles  Comments Off on Accountability for Medical Error: Moving Beyond Blame to Advocacy (Review)
Aug 142011
 

Accountability for Medical Error: Moving Beyond Blame to Advocacy. CHEST 2011;140:519-526.  Bell et al’s great essay on the dysfunctional mechanics and culture of liability / safety / blame surrounding medical errors in hospitals and our medical care system in general. They propose steps toward “collective accountability,” e.g., we MDs should sit on hospital safety committees. But [… read more]

Bronchiolitis Obliterans Syndrome: The Final Frontier for Lung Transplantation (Review)

 Lung Transplantation, Review Articles  Comments Off on Bronchiolitis Obliterans Syndrome: The Final Frontier for Lung Transplantation (Review)
Aug 082011
 

Bronchiolitis Obliterans Syndrome: The Final Frontier. No, it’s not the new Star Trek movie featuring a breathless William Shatner. It’s Todd JL, Palmer SM’s review on BOS, the lung transplantation scourge, in CHEST 2011;140:502-508.