CHEST Archives - Page 3 of 7 - PulmCCM
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Mar 172012
 

Managing Anticoagulation in the Perioperative Period from the ACCP Guidelines, 9th Ed. The ACCP‘s new 9th edition of their authoritative clinical practice guidelines for prevention and treatment of venous thromboembolism (VTE) were published in February 2012. PulmCCM is not affiliated with ACCP. These summaries are only appropriate for those who have read and are familiar with [... read more]

Mar 112012
 

Preventing DVT and PE in Nonsurgical Patients from the ACCP Guidelines, 9th Ed. The ACCP‘s new 9th edition of their authoritative clinical practice guidelines for prevention and treatment of venous thromboembolism (VTE) were published in February 2012. PulmCCM is not affiliated with ACCP. The commentary provided here is only appropriate for use as a reference by those [... read more]

Mar 082012
 
Obstructive sleep apnea increases risk for postop complications (CHEST)

Mayo investigators reported back in 2001 that people with obstructive sleep apnea had a higher rate of perioperative complications including hypoxia and longer lengths of stay. Since then, there have been other signals that this is a real phenomenon, but perhaps surprisingly, the evidence hasn’t exactly piled up to unequivocally prove the intuitive point. That’s [... read more]

Mar 052012
 

Starting and Managing Warfarin/Coumadin for Initial Treatment of DVT/PE from the ACCP Guidelines, 9th Ed. The ACCP’s new 9th edition of their clinical practice guidelines for prevention and treatment of DVT/PE were published in February 2012.  Here we review their update on how to start a patient on warfarin (Coumadin) for deep venous thrombosis or pulmonary [... read more]

Mar 022012
 
Walk to wean: Early mobilization for ventilated patients (Review, CHEST)

Daily interruption of sedation (daily awakening or sedation holidays) works like a charm to get patients off the ventilator, faster. After proving that a decade or so ago, practice-changers John Kress and William Schweickert have turned their attention to early mobilization as the next intervention that could help mechanically ventilated patients escape the ventilator faster. [... read more]

Mar 012012
 

American College of Chest Physicians (ACCP)’s Guidelines for Diagnosis & Management of DVT / PE, 9th Ed. The ACCP‘s new 9th edition of their authoritative clinical practice guidelines for prevention and treatment of venous thromboembolism (VTE, DVT, PE) were published in February 2012. PulmCCM is not affiliated with ACCP; the commentary here is only appropriate for use as a reference [... read more]

Feb 292012
 
"First dibs" on patients by sleep docs increased CPAP adherence (CHEST)

In the face of criticism from insurers and the government for a perceived excessive zeal for profits, and mounting evidence that uncomplicated obstructive sleep apnea (OSA) can be diagnosed at home and managed by primary physicians, you can’t blame sleep specialists for feeling down-in-the-mouth lately. Sushmita Pamidi et al report some brighter news in the [... read more]

Feb 262012
 

I knew I smelled something fishy about this paper when I read and commented on it last year.  Now, Chest reports they’re giving this study a burial at sea, after the authors could not produce actual data supporting the trial. To help set the record straight: Chest published a retrospective study in March 2011, “Chest Tube [... read more]

Jan 272012
 

C. difficile has always been a foul and disgusting adversary, but lately it’s becoming more formidable and deadly, according to Linda Bobo, Erik Dubberke and Marin Kollef. A few highlights of this excellent review: C.diff infections (CDI) have more than doubled since 2001, to > 340,000 discharges in 2008. Attributable mortality is 6-7%, but may [... read more]

Jan 212012
 
Omitting heparin prophylaxis in first 24 ICU hours associated with higher mortality (CHEST)

As you know, the risk for DVT and PE in the ICU are high. How high? Depends on how you count them. Asymptomatic, ultrasound-surveillance-detected DVTs have an incidence of 5-10% during the ICU stay (from the PROTECT trial and a 2005 series), even when patients receive proper thromboprophylaxis. The incidence is even higher (up to 80%) in trauma [... read more]

Jan 152012
 

Himani Gupta, Prateek Gupta, and Lee Morrow of Creighton have done us all a favor by mining a national database (the National Surgical Quality Improvement Program) to create and validate a risk calculator for perioperative pulmonary complications, which they unveil in the November CHEST. Pulmonologists are consulted every day to weigh in on the risk [... read more]

Jan 122012
 
How to cure abdominal compartment syndrome without surgery (CHEST)

Intra-abdominal hypertension (defined as a sustained urinary bladder pressure > 12 mm Hg) may be an under-recognized problem in the ICU, especially in patients after abdominal surgery or who have gone massive volume resuscitation with blood and/or fluids (think hemorrhage, burns and sepsis). When high abdominal pressures (> 20 mm Hg sustained) cause organ failure and/or [... read more]

Jan 082012
 
Early tracheostomy doesn't improve outcomes ... much (Meta-analysis, CHEST)

[poll id="3"] A 2005 meta-analysis of 5 studies (n=406) concluded that early tracheostomy reduced need for mechanical ventilation and ICU days. But then a 2006 randomized trial in trauma patients found no benefit to early trach, and an underpowered 2008 RCT also found no benefit. In a new meta-analysis and systematic review of 7 trials (n=1,044), Fei [... read more]

Jan 082012
 
Elderly critically ill who survive ICU rationing live well (CHEST)

Many argue that as a limited resource serving unlimited needs, medical care is “rationed” by definition, and ICU resources (being more limited and expensive) are simply more overtly rationed. For example, in France, ICU admission is often denied to the very elderly critically ill, explicitly because of their age (this happens in the U.K., too, probably). In the U.S., [... read more]

Jan 072012
 

One thing I thought I knew was that overweight and obesity cause coronary artery disease and make it worse. People with CAD who are obese should lose weight … right? Recent research shows it’s not that simple (although the answer is still “yes, probably”). Did you know about the “obesity paradox?” Or the “lean paradox,” [... read more]

Jan 012012
 

Ultrasound is the future. It’s even better than that: it’s the present. So say proponents Seth Koenig, Mangala Narasimhan and pioneer & innovator Paul Mayo in this month’s CHEST review. They endorse a “paradigm shift” meaning, in effect, you get professionally trained on this highly versatile, effective, and immediate-results-providing modality and integrate it into your routine [... read more]

Jan 012012
 

Each individual episode of critical illness produces a mushroom cloud of data, most of which dissipates without being recorded at all (think realtime infusion rates of vasopressors and continuous ECG monitoring). A few large databases capture outcomes data from multiple participating hospitals (like the National Inpatient Sample), and the new MIMIC-II integrated data system can [... read more]

Dec 262011
 

Walkey et al combined 8 randomized trials including 1,641 people with MRSA pneumonia, and found no significant differences between those treated with linezolid or vancomycin in survival, resolution of clinical pneumonia, eradication from sputum of MRSA, or adverse events. Authors dispute linezolid’s supposedly higher lung penetration, pointing out that that dogma evolved from studies of healthy people; [... read more]

Dec 262011
 

Moores LK et al. Current Approach to the Diagnosis of Acute Nonmassive Pulmonary Embolism. CHEST 2011;140:509-518.  Review. Where is the best area under the curve, or the “overdiagnosis sweet spot?” It seems no approach gets us off the hook as we seek to avoid anticoagulating people without PEs (without missing any, of course): CT-angiography  is more sensitive [... read more]

Dec 262011
 

Wijesinghe et al randomized and crossed-over 24 people who were recently diagnosed with obesity hypoventilation syndrome to breathe either 100% oxygen or room air for 20 minutes on 2 separate days, while measuring their minute ventilation, expired tidal pCO2, and dead space-to-tidal volume ratio. In 44% of patients, pCO2 increased by at least 4 mm [... read more]