Jul 242011
 

Hashimoto et al randomized 95 adults taking chronic prednisone for severe asthma to usual care or home-tapering guided by spirometry, exhaled nitric oxide (from hand-held devices) and a symptom diary. The self-tapered group used significantly less prednisone without a worsening in symptoms (primary endpoint), hospitalizations or exacerbations (2' endpoints). (n=95) Thorax 2011;66:514-520.

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Self-tapering of oral steroids in severe asthma