Nebulized hypertonic saline reduces inflammation in CF bronchi

Although universally recommended, there was no evidence that nebulized hypertonic saline actually reduced inflammation in the airways of cystic fibrosis patients. Reeves et al proved that it does (specifically, by disrupting IL-8 from glycosaminoglycan matrices before they can recruit neutrophils by chemotaxis to wreak havoc). AJRCCM 2011;183:1517-1523.

You may also like -

Pulmonary Hypertension Update, Part 1: Classification & Diagnosis (Review, JAMA)FDA approves ivacaftor (Kalydeco), new cystic fibrosis drug (Guess what it costs?)Nebulized Gentamicin Helped non-CF Bronchiectasis PatientsAerosolized levofloxacin for CF patients with chronic PseudomonasAirway remodeling and its relationship to inflammation in cystic fibrosis. (Review)