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In case there was any question, no you can't use the femoral vein to collect ScvO2 samples. Davison et al found a bias of 4% between femoral and nonfemoral sources in 39 critically ill patients (with an interestingly wide standard deviation of 12% in blood obtained from either source). In more than half the patients, the two sources differed by >5%, enough to change management. Lactate was consistent across femoral and nonfemoral sources. CHEST 2010;138:76-83. FREE FULL TEXT