Ventilation strategy using low tidal volumes, recruitment maneuvers, and high PEEP for ARDS/ALI (RCT) - PulmCCM
Advertisement
Jan 242008
 

Meade MO et al. (Lung open ventilation study investigators) Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: a randomized controlled trial.  JAMA 2008; 299:637-45. Higher PEEP provided no benefit in 28-day mortality (28 vs 32%, p = 0.2), although it reduced refractory hypoxia (~5% vs. 10%, p = 0.01). The target plateau pressure was <40 cm H2O, higher than the usual 30. FREE FULL TEXT

Liked this post? Get a weekly email update (no spam, ever), and explore our library of pulmonary and critical care guidelines, practice updates and review articles.

PulmCCM is an independent publication, not affiliated with or endorsed by any other organization, society and/or journal referenced on the website.

Leave a Comment